
About the game
ANNO: Mutationem is an action-adventure game with RPG elements set in a cyberpunk world, featuring a unique mix of pixelated 2D & 3D graphic style with a rich, dark and bizarre plot.
Welcome to the neon-covered, 2D-meets-3D Cyberpunk world of ANNO: Mutationem. In this Action-Adventure game with RPG elements you become Ann: a highly-skilled combat-trained lone wolf on a personal mission in the giant Metropolis, full of sinister mega-corporations, mysterious fringe groups and creatures more bizarre than words can express.
【Explore and discover】
This is a world full of surprises waiting for you to find out! While going thru the main story you can chat with a Cyborg corgi, take on a part-time bartender job, hunt down vicious criminals reveal the true face of a trending V-streamer! By exploring diverse locations such as neon Noctis Town, an off-shore cargo ship and huge underground structures, players are free to go as they please and act as they want.
【Showing new perspective】
Unique 2D-to-3D gameplay, seamless switching between 2D Action n' Platforming and 3D Exploration to interact with the world and its inhabitants. Let's dive into pixel gaming from another perspective!
【Ann kicks Ass】
Ann will slash, shoot, combo, grenade-throw & ground-pound her way through hordes of enemies and huge bosses. From great swords to double blades, from pistols to rocket launchers and uppercuts, time to become the one-girl army you always knew you had in you.
【Try to finish the jigsaw】
A grand story, befitting a rich and dark cyberpunk décor, featuring our main hero Ann Flores and her trusty hyper hacker side-kick Ayane on a personal mission to find out where her missing brother has gone to. Little do the two know just what they will unravel…
【Please arm yourself to teeth】
Collect, buy or craft items & upgrade Ann's stats, skills and gear. Use chips to modify any kind of weapon you find. Equip Ann and make her combat-ready for all enemies (both humanoid and not…) that are about to head her way.
Description from the publisher’s Microsoft Store listing.
Trailer
Official trailer · PlayStation on YouTube · Watch on YouTube ↗Loads from youtube-nocookie.com only when you press play.
Screenshots
Tap to expand · from the Microsoft Store listingAlso on Game Pass
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Game details and art come from each game’s official Microsoft Store listing (cover images are cropped from those official images, or from publisher press kits, with our title overlay; nothing is AI-generated); art © the respective publishers, used for editorial review. Game Pass membership from Microsoft’s public Game Pass catalog, checked Sep 29, 2026. Critic scores appear only where a real aggregate exists; otherwise “Not yet reported”.